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Renewal of thickness and functionality of the endometrium by using the patient's own stem cells.
Endometrial regeneration with autologous mesenchymal stem cells is a reliable, safe, and effective method of treatment.
Inna Sapozhak, MD, gynecologist, endocrinologist, fertility specialist, co-author of the treatment method.
For a successful pregnancy, not only high-quality embryos are needed, but also a healthy and mature woman's endometrium. It ensures the implantation of the embryo and the beginning of a pregnancy. Asherman's syndrome, chronic endometritis, polyps, endometrial hypoplasia, uterine synechiae, low endometrial thickness are the most common causes of infertility.
The endometrium is a dynamic, continually regenerating tissue, a unique model of physiological angiogenesis in adult women.Doctors and biotechnologists at GOOD CELLS are using an innovative and effective treatment for endometrial renewal.
As a part of the treatment program, we offer endometrial regeneration using autologous stem cells. After the renewal of the endometrium's thickness and functionality, the program can be continued by natural conception or in vitro fertilization/IVF.
The treatment is indicated for:
● women who have experienced several failed IVF programs due to uterine factor;● women diagnosed with Asherman's syndrome (to stage III);● women diagnosed with female infertility caused by uterine hypoplasia.
What can you expect?
The treatment is based on using native (autologous) mesenchymal stem cells. The potential of our laboratory lets us grow a required quantity of cells in less than a month! In the next cycle (after the sailing of biomaterial), we can perform the endometrial regeneration procedure and help you reach the desired pregnancy using IVF or natural origin.
Consultation with a manager
Contact our managers with no obligations on your side. At this step, we gather your medical information and confirm the diagnosis. After that, we'll arrange a free online or offline consultation with the doctor.
Online/offline consultation with a doctor
After making a decision, you can start planning a visit to the clinic. The treatment is performed in our clinical bases in Kyiv, Ukraine. You'll need to visit the clinic three times during the whole treatment: for the consultation, sampling of the endometrial tissue, and the injection. The latter usually takes place on the 21st day after the sampling.
First visit to the clinic
The first visit to the clinic for diagnosis verification includes general diagnostics, analysis, and checkup.
Second visit to the clinic
During your second visit to us, we take the material sampling using endometrial biopsy in the proliferative phase of the cycle. It is a painless procedure that lasts less than two hours.
Stem cell product
After the biopsy, our team of biotechnologists prepares the therapeutic dose of your own stem cells. In our laboratory, we will cultivate your stem cells from the sample of endometrial tissue, grow the required quantity of cells, test, and produce the stem cell product for your treatment. Usually, the production term is about 21 days.
Injection of the cellular product, the regeneration phase
The procedure takes place at the beginning of the menstrual cycle (proliferative phase). During the procedure, we return your own stem cells (cultivated and tested) back into the uterine cavity, thereby stimulating the regeneration process. The process is painless and takes up to 2 hours.
Depending on your medical case, in the absence of other causes of infertility by both partners, pregnancy can occur in one cycle naturally or as a result of IVF, even if previously you had unsuccessful attempts.
You can also choose the IVF program with your embryos from our partner, Ilaya clinic. The same fertilization specialist can accompany this program.
“My husband and I have been planning a pregnancy since 2002. It did not happen so we went to the doctors. I was diagnosed with polycystic ovarian syndrome. We tried many different techniques, but the problem was with the endometrium and then we decided to use the stem cells!Today I am pregnant and I know that this decision was fateful for us."
Woman, 38, birth of daughter
“I had 3 ectopic pregnancies and removed Fallopian tubes, 5 mm endometrium which did not grow further. We received treatment since 2015 and wanted a child since 2008. I really wanted to give birth without surrogacy. We didn't give up and won together with the doctor. The main thing is to not be afraid and believe, try something new. Thanks to my doctor and husband for the support."
Woman, 41, pregnant
In 2020, the GOOD CELLS team, including Alyona Zlatska, Inna Sapozhak, Olga Gubar, and Anzhela Rodnichenko, published a scientific article in the authoritative British Journal of Medical Case Reports "Application of autologous endometrial mesenchymal stromal/stem cells increases thin endometrium receptivity: a case report". Read more in the original article.