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Diabetic foot


It is possible to improve foot tissue by boosting innervation and blood supply with the help of stem cells.

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Stem cells take care of the health of your feet!

The effectiveness of such treatment can vary depending on the degree of the patient's decompensation and is between 40 and 60%.

Roman Sulik, MD, coordinator of cell therapy programs, neurologist of the highest qualification category

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How to treat diabetic foot?

The cause of diabetic foot is a violation of the proper innervation and blood supply to tissues in patients with diabetes.
Thus, the main treatment tactic is restoring peripheral vessels and nerves, in our case, the foot.
GOOD CELLS offers treatment of diabetic foot using adipose mesenchymal stem cells (MSCs). The administration of these cells improves the overall course of diabetes, helps restore vascular endothelium, and improves metabolism in the foot's soft tissues. Administration of neural crest-derived multipotent stem cells will support the restoration of nerve endings in the foot.

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Treatment of diabetic foot

This treatment is indicated for patients over 18 y.o. with confirmed type 2 diabetes mellitus complicated by diabetic foot.
Contraindications:
oncological diseases or their presence in the anamnesis for the last five years; pregnancy; mental disorders and psychological instability; alcohol and drug addiction.

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Diabetic foot treatment with stem cells

As a result of the treatment, you will feel an improvement in the disease manifestation:
reduction of foot pain; reduction of edema; reduction of trophic disorders, such as skin discoloration; reduction of the need for drugs against diabetes because the cells can stabilize metabolic processes both locally and in all tissues of the body.
The results of treatment arise from the restoration of blood supply and recovery of nervous tissue.

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The treatment process

  • 1. Consultation with a manager

    Contact our managers. At this step, we gather your medical information and confirm the diagnosis. After that, we'll arrange a free online or offline consultation with a doctor.

  • 2. Consultation with a doctor 

    A personal consultation with a doctor is an opportunity for you to find out all details of the program and get an individual prognosis. All the medical information you provide will be carefully reviewed so that you get the most effective treatment. The procedures take place in our clinical institutions in Kyiv, Ukraine.
    The course of the treatment is developed individually and lasts from 1 to 7 days.

  • 3. Checkup

    During the checkup, the doctor assesses your readiness for cell therapy. If the assessment is positive, biological materials are taken. Depending on your doctor's recommendations, you may be prescribed your own* or donor stem cells.
    * If you are prescribed the treatment with your own cells, you will have an ear punch biopsy performed under local anesthesia in an operating room. The procedure lasts for 15 minutes. The punch depth is up to 4 mm, and the diameter is up to 3 mm.

  • 4. Preparation of the stem cell product

    OWN CELLSAfter the biomaterials are collected, our team of biotechnologists will prepare a therapeutic dose of stem cells. In our laboratory, we will select stem cells from your sample, grow the required number of cells, test them, then create a stem cell product for your treatment. Usually, the production takes up to 21 days.
    DONOR CELLSAccording to the doctor's prescription, the biotechnologist will select a ready-made and pre-tested sample of donor cells from our cryobank in the required quantity. In this case, cell injection can happen right after diagnosis and drug preparation.

  • 5. Start of treatment

    The first visit to the clinic to confirm the diagnosis includes analysis, and diagnostics (ultrasound of the thyroid gland, ultrasound of the pelvic organs, ultrasound of the abdominal cavity, ECG, diagnosis of the affected target organs).

  • 6. Pharmacological therapy

    Based on the diagnostic results, your doctor will prescribe metabolic therapy to improve the functioning of the affected tissues. The doctor will also prepare you for cell therapy with the help of intravenous infusion, intramuscular injections, and correction of sugar levels (in case of severe disorders).

  • 7. Injection of the cellular product, the regeneration phase

    As part of the treatment, you will receive intravenous cell therapy, as well as a local injection into the foot and leg. Depending on the course of the disease, additional areas may be involved, such as the abdomen.

  • 8. Medical report and reducing of the basic treatment

    You will be provided with a medical report that provides the diagnosis, the results of diagnostics (clinical, laboratory, and instrumental), the treatment process, and further recommendations. The doctor will check your condition, select the necessary treatment, or adjust the one prescribed to you at the time of arrival at the clinic.

  • 9. Keeping in touch

    Throughout the program, you will have a personal manager who will ensure the best communication between you and the clinic. After treatment, our patients are advised to maintain contact with us. We'll ask you to fill out a questionnaire in 3 and 6 months after the treatment to evaluate the progress and answer all questions.

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Feedback from our patients

Find out why patients choose an innovative method of treating diabetic foot from GOOD CELLS!

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Scientific evidence

In addition to our own practical experience in treating ulcers that occur during the diabetes progression, numerous foreign studies have shown the usefulness of using cellular products in the treatment of diabetic foot. The most commonly used cells are bone marrow MSCs, placental MSCs, umbilical cord MSCs, MSC derivatives such as conditioning medium, exosomes. In most of the studied cases, the use of cellular products led to:
 complete healing of ulcers, while traditional treatment, allowed to reduce the area of ​​the wound by approximately 70%; preservation of foot function after transplantation; restoration of blood supply to the limb; the disappearance of pain at rest.
There were no complications throughout the observation period.
More about the results of the research are in the links below:
1. Becerra-Bayona S.M., Solarte-David V.A., Sossa S.L. et al. Mesenchymal stem cells derivatives as a novel and potential therapeutic approach to treat diabetic foot ulcers // Endocrinology, Diabets&Metabolism, 2020. https://doi.org/10.1530/EDM-19-01642. Maksimiva N, et al. Early passage autologous mesenchymal stromal cells accelerate diabetic wound re-epithelialization: A clinical case study // CCytotherapy 2017. https://doi.org/10.1016/j.jcyt.2017.08.0173. Debin Lu et al. Autologous transplantation of bone marrow mesenchymal stem cells on diabetic patients with lower limb ischemia // J of Medical Colleges of PLA, 2008. https://doi.org/10.1016/S1000-1948(08)60031-3